Table 1.
Selected baseline characteristics of patients with visceral leishmaniasis by treatment. Values are means (SD) unless stated otherwise
| Aminosidine
|
Sodium stibogluconate 20 mg/kg/day (n=30) | Comparison (P value)* | |||
|---|---|---|---|---|---|
| 12 mg/kg/day (n=30) | 16 mg/kg/day (n=30) | 20 mg/kg/day (n=30) | |||
| Male:female ratio | 18:12 | 18:12 | 23:7 | 24:6 | 0.19 |
| Age (years) | 29.83 (14.77) | 23.73 (12.02) | 29.10 (14.67) | 26.07 (12.58) | 0.28 |
| Weight (kg) | 37.85 (12.80) | 35.87 (11.39) | 37.63 (12.53) | 37.25 (12.44) | 0.60 |
| Duration of illness (No of days with fever) | 73.57 (57.07) | 69.73 (49.28) | 90.47 (59.20) | 62.33 (40.50) | 0.2 |
| Spleen size (cm) | 5.96 (3.59) | 6.44 (3.70) | 6.36 (4.70) | 5.55 (3.45) | 0.80 |
| Haemoglobin concentration (g/l) | 86 (14.2) | 76 (20.1)† | 82.5 (10.3) | 89.2 (13.1)† | 0.0064 |
| White cell count (109/l) | 4.05 (1.16) | 3.59 (0.89) | 4.04 (1.07) | 4.15 (1.13) | 0.19 |
| Platelet count (109/l) | 210 (66)† | 178 (34) | 168 (56)† | 178 (50) | 0.016 |
| Albumin concentration (g/l) | 30.7 (5.0) | 30.7 (3.8) | 29.9 (4.0)† | 33.2 (5.2)† | 0.015 |
| Parasite burden (grade) | 2.20 (0.96) | 2.03 (0.96) | 2.40 (0.81) | 1.93 (0.74) | 0.18 |
*
Calculated from one way analysis of variance, except for male:female ratio calculated from χ2 test.
†
Significant on Tukey’s honest significance difference.