Table 5.

Relationship between 8 common mutation types and scoliosis

		Model 1		Model 2
		OR (95% CI)	p	OR (95% CI)	p
MECP2	R294X	Ref		Ref
mutation	R106W	7.47 (1.43, 38.93)	0.017	3.83 (0.68, 21.59)	0.128
	R133C	2.83 (0.69, 11.59)	0.147	4.48 (0.99, 20.10)	0.050
	T158M	8.40 (2.73, 25.87)	0.000	5.58 (1.71, 18.27)	0.005
	R168X	9.18 (2.83, 29.81)	0.000	6.59 (1.89, 22.92)	0.003
	R255X	8.21 (2.61, 25.83)	0.000	5.16 (1.54, 17.30)	0.008
	R270X	13.29 (3.64, 48.56)	<0.0001	8.28 (2.02, 33.91)	0.003
	R306C	2.42 (0.68, 8.66)	0.173	2.11 (0.53, 8.44)	0.290
Motor-behavioral assessment				1.06 (1.03, 1.08)	<0.0001
Walking	Acquired <18 mo/apraxic gait			Ref
	Acquired ≥18 mo or lost or never			2.58 (1.16, 5.71)	0.020
Constipation	No			Ref
	Yes			1.30 (0.61, 2.78)	0.500

Model 1, logistic regression model for P (having scoliosis = 1) adjusting for age; model 2, logistic regression model for P (having scoliosis = 1) adjusting for age and significant clinical parameters.