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. Author manuscript; available in PMC: 2010 Apr 9.
Published in final edited form as: Arch Gen Psychiatry. 2010 Apr;67(4):380–387. doi: 10.1001/archgenpsychiatry.2010.13

Table 3.

Areas of increased activation in response to contrasts of interest

Contrast Region BA Side X
RL
Y
AP
Z
IS
Between
Groups t
Vox d Low-
Risk t
High-
Risk t
Anticipation of Gain vs.
Non-incentive
(Gain-Non-incentive
Anticipation)
High-Risk > Low-Risk Insula 13 R 38 −15 8 −3.24 18 1.27 −3.459 0.808
Low-Risk > High-Risk Putamen L −19 0 4 3.84 17 1.51 5.535 0.406
Insula 13 L −34 −11 16 3.61 12 1.42 2.304 −2.865
Anticipation of Loss vs.
Non-incentive
(Loss-Non-incentive
Anticipation)
Low-Risk > High-Risk Lentiform Nucleus/
Globus Pallidus
L −18 0 7 3.81 74 1.49 3.831 −1.855
Mid Cingulate Gyrus 24 L − 4 4 27 2.94 16 1.15 3.189 −0.923
Outcome of Gain vs.
Nongain
(Gain-Nongain Outcome)
Low-Risk > High-Risk Ant Cingulate Gyrus 32 R 11 19 27 4.44 144 1.74 2.974 −1.103
Post Cingulate
Gyrus
23 L 0 −26 31 4.41 83 1.73 2.735 −2.705
Mid Cingulate Gyrus 24 L −11 4 34 4.45 47 1.75 3.753 −0.919
Putamen/
Lentiform Nucleus
L −23 −4 4 3.50 17 1.37 1.900 −1.670
Ant Cingulate Gyrus 32 L −4 19 42 2.90 13 1.14 1.860 −2.400
Ant Thalamic
Nucleus
R 8 −4 12 3.35 11 1.31 1.567 −2.034
Ant Cingulate Gyrus 32 L −11 34 19 4.72 11 1.85 0.972 −3.130
Outcome of Loss vs
Nonloss
(Loss-Nonloss Outcome)
High-Risk > Low-Risk Cingulate Gyrus L 0 23 27 −2.93 10 1.15 0.525 3.280
Low-Risk > High-Risk Caudate R 17 19 1 4.30 15 1.69 1.262 −3.306
Putamen L −15 15 −7 2.90 11 1.14 0.236 −2.943

Activations with greater than 10 contiguous voxels reported, thresholded at p= .05. R = right; L = left; BA = Brodmann’s Area; Coordinates are in Talaraich-Tournoux space; x, y, z coordinates refer to left/right (x: negative = right), anterior/posterior (y: negative = anterior), and inferior/superior (z: negative = inferior); Max t indicates t score at the peak activation of each loc; Vox indicates number of voxels in cluster; d indicates effect size (Cohen’s d).