Fig. 2.
PTH-βarr increases lumbar spine BMD. (A and B) Lumbar spine and (C and D) femoral BMD of male WT and β-arrestin2−/− mice treated with vehicle (Veh), 1-34), or PTH-βarr was determined by dual-energy x-ray absorption. Mice were treated starting at 9 weeks of age. Data represent the mean percent change from baseline BMD ± SEM of measurements taken from at least seven male mice. *P < 0.05; **P < 0.01 compared with vehicle-treated WT mice. †P < 0.05, ††P < 0.01, †††P < 0.001 compared with vehicle-treated β-arrestin2−/− mice; significance was determined with one-way ANOVA with Bonferroni multiple comparisons post test.