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Conservation of consensus exceptional words. Fraction of words versus Pfam-A HMM entropy (variation) in half bits. The most conserved sites are on the right with low entropy values. (A) Consensus overrepresented exceptional words [observed, 1up5, (i + 1) spacing] compared randomly sampled words (sampled). (B) Underrepresented words. Error bars report the 95% confidence intervals obtained by 500 bootstraps of the Pfam-A library with replacement.
