TABLE 1.
Symptoms |
Group A (observation) |
Group B (rabeprazole) |
Group C (hydrotalcite) |
Group D (combination) |
||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
Pre | Post | P | Pre | Post | P | Pre | Post | P | Pre | Post | P | |
Epigastric pain | 3.24±0.71 | 3.39±0.53 | 0.054 | 3.24±0.79 | 2.39±0.86 | 0.041* | 3.32±0.08 | 2.06±1.00 | 0.033* | 3.36±0.65 | 1.88±0.86 | 0.035*† |
Heartburn | 3.31±0.64 | 2.91±0.59 | 0.061 | 3.31±0.64 | 2.21±0.95 | 0.031* | 3.23±0.69 | 1.96±0.07 | 0.026* | 3.12±0.67 | 1.72±0.79 | 0.041*† |
Bloating | 3.27±0.86 | 3.10±0.94 | 0.093 | 3.22±0.71 | 2.16±0.91 | 0.029* | 3.21±0.70 | 2.06±0.91 | 0.031* | 3.25±0.68 | 1.69±1.01 | 0.022*† |
Bitter taste | 3.25±0.78 | 3.22±0.99 | 0.075 | 3.24±0.71 | 2.27±0.96 | 0.024* | 3.29±0.73 | 2.16±0.92 | 0.013* | 3.10±0.64 | 1.75±0.79 | 0.032*† |
Pre- and post-treatment data presented as mean ± SD. Symptom scores ranged from 0 (not present) to 5 (very severe).
P<0.05 compared pre- and post-treatment in each group;
P<0.05 compared among the four groups