. Author manuscript; available in PMC: 2010 Apr 9.

Published in final edited form as: Vet Pathol. 2009 May 9;46(5):1003–1014. doi: 10.1354/vp.08-VP-0254-N-FL

Table 1.

Mouse strains used for inoculation of adult T-cell lymphoma/leukemia cells.

	NOD/SCID	NOD/SCID^β2m−/−	NOD/SCID^{IL2-Rγ−/−}
Mutation/gene deletion	Catalytic subunit of the DNA-activated protein kinase (PRKDC) gene	Catalytic subunit of the DNA-activated protein kinase (PRKDC) gene	Catalytic subunit of the DNA-activated protein kinase (PRKDC) gene
		Beta-2 microglobulin gene	Gamma chain of interleukin-2 receptor gene
Deficient immune function	Lack B and T cells	Lack B and T cells	Lack B and T cells
	Reduced natural killer cell activity	Lack natural killer cell activity	Lack natural killer cell activity
			Reduced interferon gamma production