Figure 1).

Ratio of clinical success rates over comparators in randomized controlled trials among 63 monotherapy regimens for complicated intra-abdominal infections. Data are expressed as mean ± 95% CIs of study regimens over the comparator in each trial. Number of studies for the antimicrobial groups are shown in parentheses. Second-generation (gen)cephalosporins include cefoxitin, cefotetan, cefuroxime and cefamandole. Third-gen cephalosporins include cefoperazone with/without sulbactam. Antianaerobic fluoroquinolones include moxifloxacin, clinafloxacin and trovafloxacin. Data were compiled from published results of prospective randomized comparative trials (49,52,62,70,95,96,98,100–104,110,116–120,129,217–243)