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. 2010 Spring;21(1):11–37. doi: 10.1155/2010/580340

TABLE 9.

Clean-contaminated abdominal surgeries for which antibiotic prophylaxis is indicated

Colorectal surgery

Elective colon resection, low-anterior resection of the rectum and abdominal perineal resection of the rectum also require a specific colon preparation to empty the bowel contents and reduce the amount of microorganisms
Appendectomy

Perforated, gangrenous or necrotizing appendicitis
Esophageal surgery

If obstruction is present
Sclerotherapy of esophageal varices
Esophageal dilation
High-risk gastroduodenal surgery

Situations in which gastric acidity is decreased
Cancer, active bleeding
Decreased gastroduodenal motility (obstruction, obesity)
Small-intestine surgery

High-risk biliary tract surgery

Age >70 years, diabetes, obesity
Acute cholecystitis, cholelithiasis or obstructive jaundice
Nonfunctional gallbladder (excluding nonurgent laparoscopic cholecystectomy in low-risk patients)
Open biliary tract surgery