Bacteria | Ceftazidime/cefepime | Ceftriaxone/cefotaxime | Fluoroquinolones* | Clindamycin | Aminoglycosides† | Ertapenem | Imipenem/meropenem | Pip-tazo/ticar-clav | Linezolid | Vancomycin | Tige-cycline |
---|---|---|---|---|---|---|---|---|---|---|---|
Staphylococcus aureus (MS) | + | ++/+++ | +++ | ++++ | ++ | ++++ | ++++ | ++++ | ++++ | ++++ | ++++ |
S aureus (MR) | – | – | – | +/++ | + | – | ++ | –/+ | ++++ | ++++ | ++++ |
Staphylococcus epidermidis (MS) | + | ++/+++ | +++ | +++ | + | ++ | ++++ | ++++ | ++++ | ++++ | ++++ |
S epidermidis (MR) | – | – | – | + | + | – | ++ | –/+ | ++++ | ++++ | ++++ |
Enterococcus faecalis (VS) | – | – | + | ++ | + | – | +++ | ++++ | ++++ | ++++ | ++++ |
E faecalis (VR) | – | – | – | –/+ | + | – | + | + | ++++ | – | ++++ |
Enterococcus faecium (VS) | – | – | + | –/+ | + | – | + | + | ++++ | ++++ | |
E faecium (VR) | – | – | – | –/+ | + | – | – | – | ++++ | – |
Includes ciprofloxacin, levofloxacin and moxifloxacin;
Includes gentamicin, netilmicin, tobramycin and amikacin. – Poor activity; + Limited activity and/or resistance ≥15%; ++ Moderate to good activity and/or resistance 10% to 14%; +++ Very good activity and/or resistance 5% to 9%; ++++ Excellent activity and/or resistance <5%; MR Methicillin resistant; MS Methicillin sensitive; Pip-tazo Pipercillin-tazobactam; Ticar-clav Ticarcillin-clavulanate; VR Vancomycin resistant; VS Vancomycin sensitive. Data adapted from references 216,248–255