TABLE 2.
Methicillin-resistant Staphylococcus aureus (MRSA) decolonization rates and patient outcomes
| Outcome | Hospital protocol, n=89 | Other treatment, n=98 | No treatment, n=54 | Hospital protocol vs other treatment OR (95% CI); P | Hospital protocol vs no treatment OR (95% CI); P |
|---|---|---|---|---|---|
| Overall decolonization, success/known (%) | 67/84 (80) | 48/89 (54) | 4/43 (9) | 3.3 (1.6–7.1); P=0.0004* | 36.9 (11.2–161.7); P<0.000001* |
| Short-term decolonization, success/known (%) | 63/82 (77) | 46/78 (59) | 3/38 (8) | 2.3 (1.1–4.9); P=0.018* | 37.2 (10.1–209.6); P<0.000001* |
| Long-term decolonization, success/known (%) | 33/62 (53) | 18/55 (33) | 2/32 (6) | 2.4 (1.0–5.3); P=0.039* | 16.2 (3.7–155.5); P=0.000003* |
| MRSA infection rate, present/known (%) | 16/89 (18) | 37/98 (38) | 5/42 (12) | 0.38 (0.18–0.78); P=0.003* | 1.66 (0.53–6.24); P=0.452* |
| Length of stay (days) | |||||
| Mean ± SD | 80±108 | 61±110 | 30±81 | P=0.001† | P<0.0000001† |
| First quartile | 22 | 8.5 | 3 | – | – |
| Median | 55 | 27 | 8 | – | – |
| Third quartile | 110 | 70 | 17.5 | – | – |
| Disposition | P=0.023* | P=0.097* | |||
| Expired | 11 (12) | 19 (19) | 9 (17) | – | – |
| Extramural (home hospital service) | 9 (10) | 11 (11) | 3 (5) | – | – |
| Home | 31 (35) | 44 (45) | 29 (54) | – | – |
| Nursing home | 14 (16) | 7 (7) | 8 (15) | – | – |
| Other hospitals | 11 (12) | 5 (5) | 2 (4) | – | – |
| Special care home | 0 (0) | 5 (5) | 2 (4) | – | – |
| Unknown | 13 (15) | 7 (7) | 1 (2) | – | – |
| 30-day mortality (from first-positive MRSA culture and sensitivity) | 3/89 (3) | 9/98 (9) | 7/54 (13) | 0.35 (0.06–1.45); P=0.139* | 0.24 (0.04–1.10); P=0.042* |
| MRSA-associated mortality, probable/definite (%) | 0/89 (0) | 4/98 (4) | 1/54 (2) | 0 (0.00–1.65); P=0.123* | 0 (0.00–23.66); P=0.378* |
*
Two-sided Fisher’s exact test, its generalization or χ2 test;
†
Two-sided Kruskal-Wallis test. vs Versus