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. Author manuscript; available in PMC: 2010 Apr 11.
Published in final edited form as: J Natl Cancer Inst. 2009 Feb 24;101(5):321–330. doi: 10.1093/jnci/djn513

Table 4.

Relative indices of inequality (RIIs) for education and their corresponding 95% confidence intervals (95% CIs) by geographic region and sex in the European Prospective Investigation into Cancer and Nutrition cohort (N=391,251)

Geographic region Model 1 Crude Model 2 Adjusted for current smoking Model 3 Adjusted for smoking§ Model 4 Adjusted for smoking and diet||

N* RII (95% CI) RII (95% CI) RII (95% CI) RII (95% CI)
Men
 North 530 5.42 (3.86 to 7.62) 3.49 (2.47 to 4.92) 2.87 (2.01 to 4.10) 2.84 (1.99 to 4.06)
 Germany 145 4.10 (2.19 to 7.66) 2.33 (1.23 to 4.40) 2.17 (1.14 to 4.13) 2.17 (1.14 to 4.14)
 South# 264 1.78 (1.02 to 3.11) 1.51 (0.87 to 2.64) 1.36 (0.78 to 2.38) 1.38 (0.78 to 2.38)
Pinteraction** .009 .08 .11 .13
Women
 North 557 3.93 (2.86 to 5.40) 2.29 (1.67 to 3.15) 1.88 (1.35 to 2.62) 1.84 (1.32 to 2.57)
 Germany 41 1.35 (0.43 to 4.29) 1.09 (0.34 to 3.44) 1.09 (0.34 to 3.47) 1.01 (0.32 to 3.21)
 South# 94 0.30 (0.13 to 0.71) 0.52 (0.22 to 1.20) 0.54 (0.23 to 1.24) 0.53 (0.23 to 1.23)
Pinteraction** <.001 .007 .02 .03
*

Number of lung cancer patients.

All analyses are stratified by center and age at baseline.

The model includes smoking status (never smoker [reference category], current smoker, former smoker), current quantity (continuous), a quadratic term for current quantity, and a dummy variable for missing variables for current quantity.

§

The model includes smoking status (never smoker [reference category], current smoker, former smoker), age at starting (continuous), duration of smoking (continuous in years), current quantity (continuous), a quadratic term for current quantity, two interaction terms (quantity × duration and age at starting × duration), dummy variables for missing values for age at starting, duration of smoking, and current quantity.

||

The model includes the variables in model 3, fruits and vegetables consumption (continuous variable, per 100g), and an interaction term between smoking status and fruits and vegetables consumption.

Norway, Sweden, Denmark, UK, and The Netherlands.

#

Greece, Italy, and Spain.

**

Test for interaction between geographic regions.