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. Author manuscript; available in PMC: 2010 Apr 10.
Published in final edited form as: Cell Host Microbe. 2009 Aug 6;6(3):207–217. doi: 10.1016/j.chom.2009.07.006

Figure 3.

Figure 3

Acute respiratory viral factor derived from the three experimental cohorts (HRV, RSV, and influenza) predicts subjects with culture-proven influenza infection from an independent dataset with a high degree of accuracy. The acute respiratory viral classifier built on the combined three challenge datasets was used to predict disease state (uninfected versus influenza A infection) in the literature cohort. A) Predictive capability of the acute respiratory viral factor to classify subjects with no infection (red) versus influenza A infection (blue). X-axis represents the individual subjects and y-axis represents the decision threshold. 0.5 is chosen as the threshold for generation of the subsequent ROC curves. B) Prediction of influenza A infected versus healthy hospitalized control subjects using the acute respiratory viral classifier. Classification of subjects in the literature cohort was highly accurate [100% (23/23) for influenza infected versus no infection].