Table 1.

MET mutations in lung cancer

	Observed in non-small cell lung cancer	Observed in small cell lung cancer
MET overexpression	X	X
Increased MET activity	X	X
Sma missense MET mutations
E168D	X
L229F	X
S323G	X
N375S	X	X
S178	X
L211W	X
A347T	X
E355K	X
M362T	X
Juxtamembrane missense MET mutations
R988C	X	X
T1010I	X	X
S1058P	X
Tyrosine Kinase missense MET mutations
D1304	X