FKBP5 polymorphisms rs3800373 (A–B), and rs9296158 (C–D) interact with level of reported child abuse to predict level of adult PTSD symptoms. For these polymorphisms within the FKBP5 gene, at low levels of child abuse, there are similar levels of mPSS-based PTSD symptoms, but at moderate to severe levels of abuse, the FKBP5 SNPs separately associate with differential levels of PTSD symptoms. (adapted from Binder et al., 2008)