Table 1.
Body weights and non-fasting blood glucose concentrations in normal chow and high fat diet-fed mice maintained with and without PMI-5011 treatment.
| Variable | Body weight, g | Blood glucose, mmol l−1 | ||
|---|---|---|---|---|
| Group | Before T (16-wk time point) | After T (23-wk time point) | Before T (16-wk time point) | After T (23-wk time point) |
| NC | 37.5 ± 0.57 | 36.8 ± 0.74 | 7.50 ± 0.19 | 7.67 ± 0.25 |
| NC + T | 36.9 ± 0.80 | 36.3 ± 0.74 | 7.28 ± 0.18 | 7.82 ± 0.31 |
| HFD | 52.6 ± 0.36** | 51.3 ± 0.57** | 8.58 ± 0.22** | 8.95 ± 0.50** |
| HFD + T | 53.7 ± 0.53** | 50.8 ± 0.90** | 8.59 ± 0.19** | 7.82 ± 0.33§,## |
Data are expressed as Mean ± SEM, n = 10–33 per group. NC: normal chow; T: treatment; HFD: high fat diet; *,**P < .05 and < .01 versus mice fed NC; § P < .05 versus the baseline value (16-wk time point); ## P < .01 versus untreated mice fed HFD (23-wk time point).