Table 4.
MANOVA results comparing longitudinal changes in STC and CTC motor circuits between baseline and follow-up in Controls.
| Follow-up vs. Baseline | ||||
|---|---|---|---|---|
| Controls (Non-dominant hand) | Controls (Dominant hand) | |||
| EG | IG | EG | IG | |
| Ipsilateral STC† | 0.734 | 0.517 | 0.529 | 0.269 |
| Ipsilateral CHTC†† | 0.016* | 0.575 | 0.913 | 0.757 |
| Ipsilateral CVTC††† | 0.212 | 0.438 | 0.744 | 0.749 |
| Contralateral STC‡ | 0.811 | 0.420 | 0.251 | 0.330 |
| Contralateral CHTC‡‡ | 0.126 | 0.212 | 0.139 | 0.552 |
| Contralateral CVTC‡‡‡ | 0.036* | 0.042* | 0.115 | 0.457 |
The percent of voxels activated with a t value > 1.96 (corresponding to a p = 0.05) were calculated for each ROI in the STC (BG, Th, SMA, and PMC), CHTC (CB, Th, PreMC, and SMC), and CVTC (Vm, Th, PreMC and SMC) circuits. Network analyses were performed using MANOVA with the changes in percent activation of individual ROIs as the dependent variables.
Ipsilateral STC was defined as ipsilateral BG, Th, SMA, and PMC;
Ipsilateral CHTC was defined as contralateral CB and ipsilateral Th, PreMC, and SMC;
Ipsilateral CVTC was defined as Vm and ipsilateral Th, PreMC, and SMC;
Contralateral STC was defined as contralateral BG, Th, SMA, and PMC;
Contralateral CHTC was defined as ipsilateral CB and contralateral Th, PreMC, and SMC;
Contralateral CVTC was defined as Vm and contralateral Th, PreMC, and SMC.