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. Author manuscript; available in PMC: 2011 Mar 17.
Published in final edited form as: Neuroscience. 2009 Dec 24;166(2):712–719. doi: 10.1016/j.neuroscience.2009.12.036

Table 5.

MANOVA results comparing longitudinal changes in STC and CTC motor circuits between PD and Control subjects.

PD (less-affected) vs. Control PD (more-affected) vs. Control
EG IG EG IG
Ipsilateral STC† 0.879 0.703 0.477 0.744
Ipsilateral CHTC†† 0.364 0.083 0.699 0.678
Ipsilateral CVTC††† 0.419 0.043* 0.710 0.767
Contralateral STC‡ 0.529 0.731 0.613 0.279
Contralateral CHTC‡‡ 0.654 0.406 0.611 0.603
Contralateral CVTC‡‡‡ 0.455 0.277 0.647 0.645

The percent of voxels activated with a t value > 1.96 (corresponding to a p = 0.05) were calculated for each ROI in the STC (BG, Th, SMA, and PMC), CHTC (CB, Th, PreMC, and SMC), and CVTC (Vm, Th, PreMC and SMC) circuits. Network analyses were performed using MANOVA with the changes in percent activation of individual ROIs over time as the dependent variables and PD status (PD vs. Control) as the independent variable.

†

Ipsilateral STC was defined as ipsilateral BG, Th, SMA, and PMC;

††

Ipsilateral CHTC was defined as contralateral CB and ipsilateral Th, PreMC, and SMC;

†††

Ipsilateral CVTC was defined as Vm and ipsilateral Th, PreMC, and SMC;

‡

Contralateral STC was defined as contralateral BG, Th, SMA, and PMC;

‡‡

Contralateral CHTC was defined as ipsilateral CB and contralateral Th, PreMC, and SMC;

‡‡‡

Contralateral CVTC was defined as Vm and contralateral Th, PreMC, and SMC.