Table 3.

Adjusted analyses for the association between marital status and cardiovascular disease death (% attenuation in relationships by adjustments).^a

	Deaths/N	Model 1	Model 2	Model 3	Model 4	Fully adjusted
		HR (95% CI)	HR (95% CI)	HR (95% CI)	HR (95% CI)	HR (95% CI)
Men
Married	66/4272	1.00	1.00	1.00	1.00	1.00
Single	31/788	2.71 (1.76–4.17)	2.55 (1.65–3.93)	2.70 (1.75–4.16)	2.56 (1.66–3.97)	2.44 (1.57–3.78)
		(15%)	(9.4%)	(8.1%)	(8.8%)	(15.8%)
Sep/Div	23/746	1.91 (1.17–3.14)	1.61 (0.97–2.68)	1.83 (1.11–3.01)	1.87 (1.13–3.08)	1.56 (0.93–2.63)
		(13%)	(33%)	(8.8%)	(4.4%)	(38.5%)
Widowed	25/295	2.34 (1.43–3.83)	2.17 (1.33–3.56)	2.27 (1.39–3.72)	2.27 (1.38–3.73)	2.11 (1.29–3.47)
		(11%)	(12.7%)	(5.2%)	(5.2%)	(17.2%)
Women
Married	40/4757	1.00	1.00	1.00	1.00	1.00
Single	15/743	2.06 (1.13–3.76)	2.06 (1.13–3.75)	2.03 (1.11–3.71)	1.83 (1.00–3.37)	1.84 (1.00–3.38)
		(no attenuation)	(no attenuation)	(2.8%)	(16%)	(17.2%)
Sep/Div	23/1258	2.55 (1.52–4.28)	2.22 (1.32–3.73)	2.39 (1.42–4.02)	2.50 (1.50–4.20)	2.13 (1.26–3.61)
		(3%)	(21.2%)	(10.3)	(3.2%)	(27.1%)
Widowed	35/1030	1.35 (0.83–2.20)	1.24 (0.76–2.03)	1.28 (0.78–2.10)	1.35 (0.82–2.20)	1.20 (0.73–1.97)
		(not applicable)	(not applicable)	(not applicable)	(not applicable)	(not applicable)

Values in italics refers to the relative change in the hazard ratios.

Model 1 adjusted for age, SES.

Model 2 adjusted for age, SES + health behaviours (physical activity, smoking, alcohol).

Model 3 adjusted for age, SES + distress (General Health Questionnaire-12).

Model 4 adjusted for age, SES + metabolic dysregulation (doctor diagnosed hypertension, diabetes, and Body Mass Index).

^aThe proportion of cardiovascular disease risk reduction explained by each set of factors was computed as follows: (HR_{basic model} − HR_adjusted)/(HR_{basic model} − 1) × 100.