Table 5.

Comparison of results of randomised controlled trials according to availability of data from individual patients for prophylaxis with topical and systemic antibiotics and topical antibiotics only

End points and dataset used	Topical plus systemic			Topical alone
	No of trials	Odds ratio		No of trials	Odds ratio
	(95% CI)		(95% CI)
Mortality
Aggregate and individual data	12	0.86 (0.72 to 1.02)		13	1.03 (0.84 to 1.26)
Aggregate data only	3	0.61 (0.44 to 0.86)		4	0.93 (0.57 to 1.52)
Respiratory tract infection
Aggregate and individual data	12	0.39 (0.32 to 0.47)		13	0.57 (0.47 to 0.70)
Aggregate data only	2	0.10 (0.05 to 0.21)		2	0.47 (0.19 to 1.13)