Table 3.
Relation between cytokine gene polymorphisms and development of precursory lesions of GC n (%)
| Genotype | Group I (n = 134) OR (95% CI) | Group II (n = 101) OR (95% CI) |
| IL-8-251 | ||
| TT | 1.00 | 1.00 |
| TA | 1.64 (0.96-2.79) | 2.27 (1.25-4.14) |
| AA | 2.62 (1.23-5.72) | 1.20 (0.76-1.90) |
| TA + AA | 1.81 (1.06-3.09) | 2.07 (1.16-3.69) |
| MIF-173 | ||
| GG | 1.00 | 1.00 |
| GC | 2.36 (1.38-4.02) | 1.50 (0.57-3.94) |
| CC | 1.92 (0.95-3.87) | 2.27 (1.16-4.46) |
| GC + CC | 2.07 (1.21-3.55) | 3.84 (1.58-9.34) |
OR and 95% CI were calculated by logistic regression, with no progression group as a reference group and adjusted for age, sex. OR: Odds ratio.