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. 2010 Feb 3;11(2):544–561. doi: 10.3390/ijms11020544

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© 2010 by the authors; licensee Molecular Diversity Preservation International, Basel, Switzerland.

This article is an open-access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/3.0/).

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Figure 1. — Microphotographs of different retinal sections. (A) Histological sections of control animals; (B) effects of bilateral common carotid artery occlusion (BCCAO). Extreme swelling of neuronal cell bodies and the fusion of the INL, IPL and GCL layers were observed. BCCAO caused severe overall retinal degeneration ameliorated by intravitreal injection of (C) urocortin 2, (D) diazoxide, (E) pituitary adenylate cyclase activating polypeptide and (F) the poly(ADP-ribose) polymerase inhibitor HO3089. Scale bar: 20 μm. Abbreviations: PL: photoreceptor layer; ONL: outer nuclear layer; OPL: outer plexiform layer; INL: inner nuclear layer; IPL: inner plexiform layer; GCL: ganglion cell layer.