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AAV1-FS344 treatment does not cause hypertrophy of cardiomyocytes. (A) H&E staining of cardiac muscle from boththe MCK-FSand the CMV-FS groups reveals normal cardiac muscle histology compared with nontreated controls. Scale bars, 50 μm. (B) Morphometric analysis shows similar mean ± SEM diameters of cardiomyocytes from AAV1-FS344–treated macaques (MCK-FS and CMV-FS groups) compared with untreated controls (n = 3 per group).
