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. Author manuscript; available in PMC: 2011 Mar 8.
Published in final edited form as: Biomacromolecules. 2010 Mar 8;11(3):754–761. doi: 10.1021/bm901352v

Table 1.

Physicochemical parameters of the targeted and non-targeted nanoglobular MRI contrast agents

Name Gd3+ Content (mmol Gd/g polymer) No. of Gd-DOTA monoamide chelates (%) r1/r2 [mM−1(Gd)s−1] B0=3T r1/r2 [mM−1(nanoglobule)s−1) B0=3T No. of Surface Peptide Particles size (nm)
G2-Gd(III) 1.15 (29/32; 90%) 7.22/12.75 209.38/369.75 0 ~5.2
G3-Gd(III) 1.20 (57/64; 89%) 8.03/16.40 457.71/934.80 0 ~5.8
P-G2-Gd(III) 1.18 (25/30; 83%) 7.92/10.34 198.00/258.50 (2/32; 6.3%) ~5.6
P-G3-Gd(III) 1.02 (43/61; 70%) 8.20/16.10 352.60/692.3 (3/64; 4.7%) ~6.2

Temperature of relaxivity measurements is 25 °C