Table 3.
Representative hematology values from the two surviving macaques in the high dose group *
| Day of sampling | |||||
|---|---|---|---|---|---|
| Pre (−14) | 7 | 15 | 43 | 85 | |
| WBC | 7.4 ± 2.0 | 5.2 ± 0.1 | 5.6 ± 0.1 | 5.3 ± 0.5 | 6.4 ± 1.2 |
| RBC | 5.2 ± 0.2 | 5.0 ± 0 | 5.1 ± 0 | 5.2 ± 0.2 | 5.2 ± 0.1 |
| HCT | 39.1 ± 1.5 | 38.4 ± 0.5 | 38.9 ± 0.2 | 39.1 ± 1.3 | 39.2 ± 0.3 |
| Platelets | 228 ± 5 | 224.5 ± 0.5 | 231.5 ± 7.5 | 248.5 ± 12.5 | 263 ± 11 |
| Segs | 53.2 ± 0.1 | 47.7 ± 3.5 | 43.4 ± 16.5 | 49.9 ± 16.5 | 64.6 ± 6.6 |
| Lymphocytes | 39.2 ± 1.5 | 45.2 ± 2.4 | 49.2 ± 16.1 | 41.8 ± 15.7 | 30.8 ± 6.2 |
| Reticulocytes | 0.9 ± 0 | 1.4 ± 0.3 | 1.2 ± 0.6 | 1.1 ± 0.2 | 1.0 ± 0 |
*
The data shown are the mean ± SE of representative values for the two animals surviving from the high dose group. white blood cell (WBC) count as cells/mm3; red blood cell (RBC) count as million cells/mm3; hematocrit (HCT) as percent; platelet count as ×103/mm3; segmented neutrophils (Segs) as percent; lymphocytes as percent; reticulocytes as percent.