TABLE 1.

Distinctions between effects of TNF and IL-13 on epithelial barrier function and tight junction composition

	TNF	IL-13
Ion conductance	Increased	Increased
Macromolecular flux	Increased	No change
Ion selectivity	No change	Increased PNa+
MLCK dependent	Yes	No
Claudin-2 expression	No change	Increased
Occludin endocytosis	Yes	No change
Apoptosis rate	No change	No change