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. Author manuscript; available in PMC: 2010 Nov 1.
Published in final edited form as: Dev Neurobiol. 2009 Nov;69(13):871–884. doi: 10.1002/dneu.20747

Figure 1. VEGFR expression in G93A-SOD1 and nontransgenic mouse spinal cords.

Figure 1

Immunostaining for VEGFR1 (A–B), VEGFR2 (C–D) and VEGFR3 (E–F) in nontransgenic (A, C, E) and G93A-SOD1 (B, D, F) mouse spinal cord sections. Arrows point to VEGFR expression in MNs in the ventral horn. (G) PCR on RNA isolated from G93A-SOD1 and nontransgenic control mouse spinal cords for VEGF family ligands and VEGFR RNA. Densitometry followed by one-way ANOVA and Tukey’s multiple comparison test demonstrates significant decreased expression of VEGF and VEGFR2 RNA in G93A-SOD1 spinal cords compared to nontransgenic control spinal cords (* P < 0.01). Results are normalized to actin. Scale bar 50 µm.