Table 3. Spearman's correlation between markers.
EGFR | P-EGFR | Her2 | P-Her2 | ErbB3 | PTEN | P-PTEN | PI3K | PAKT | P65 Cyto | P-p65 | p65 Nuc | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
EGFR | ||||||||||||
Rho | 1 | 0.625 | 0.424 | 0.624 | 0.565 | 0.222 | 0.631 | 0.608 | 0.666 | 0.312 | −0.028 | −0.047 |
P | 0 | 0 | 0 | 0 | 0.08 | 0 | 0 | 0 | 0.013 | 0.825 | 0.717 | |
p-EGFR | ||||||||||||
Rho | 0.625 | 1 | 0.571 | 0.727 | 0.419 | 0.438 | 0.697 | 0.715 | 0.685 | 0.413 | 0.098 | 0.034 |
P | 0 | 0 | 0 | 0.001 | 0 | 0 | 0 | 0 | 0.001 | 0.444 | 0.791 | |
Her2 | ||||||||||||
Rho | 0.424 | 0.571 | 1 | 0.45 | 0.379 | 0.523 | 0.358 | 0.599 | 0.382 | 0.228 | 0.166 | 0.017 |
P | 0.001 | 0 | 0 | 0.002 | 0 | 0.004 | 0 | 0.002 | 0.073 | 0.194 | 0.896 | |
p-Her2 | ||||||||||||
Rho | 0.624 | 0.727 | 0.45 | 1 | 0.416 | 0.197 | 0.473 | 0.582 | 0.766 | 0.306 | 0.036 | −0.06 |
P | 0 | 0 | 0 | 0.001 | 0.122 | 0 | 0 | 0 | 0.015 | 0.778 | 0.639 | |
ErbB3 | ||||||||||||
Rho | 0.565 | 0.419 | 0.379 | 0.416 | 1 | 0.189 | 0.483 | 0.579 | 0.497 | 0.236 | −0.125 | −0.146 |
P | 0 | 0.001 | 0.002 | 0.001 | 0.138 | 0 | 0 | 0 | 0.062 | 0.33 | 0.254 | |
PTEN | ||||||||||||
Rho | 0.222 | 0.438 | 0.523 | 0.197 | 0.189 | 1 | 0.323 | 0.592 | 0.129 | 0.419 | 0.232 | 0.075 |
P | 0.08 | 0 | 0 | 0.122 | 0.138 | 0.01 | 0 | 0.313 | 0.001 | 0.067 | 0.56 | |
P-PTEN | ||||||||||||
Rho | 0.631 | 0.697 | 0.358 | 0.473 | 0.483 | 0.323 | 1 | 0.704 | 0.592 | 0.369 | 0.158 | 0.022 |
P | 0 | 0 | 0.004 | 0 | 0 | 0.01 | 0 | 0 | 0.003 | 0.215 | 0.863 | |
PI3K | ||||||||||||
Rho | 0.608 | 0.715 | 0.599 | 0.582 | 0.579 | 0.592 | 0.704 | 1 | 0.586 | 0.432 | 0.208 | −0.026 |
P | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0.102 | 0.841 | |
P-AKT | ||||||||||||
Rho | 0.666 | 0.685 | 0.382 | 0.766 | 0.497 | 0.129 | 0.592 | 0.586 | 1 | 0.301 | 0.038 | 0.019 |
P | 0 | 0 | 0.002 | 0 | 0 | 0.313 | 0 | 0 | 0.016 | 0.768 | 0.884 | |
p65 cyto | ||||||||||||
Rho | 0.312 | 0.413 | 0.228 | 0.306 | 0.236 | 0.419 | 0.369 | 0.432 | 0.301 | 1 | 0.528 | 0.115 |
P | 0.013 | 0 | 0.073 | 0.015 | 0.062 | 0.001 | 0.003 | 0 | 0.016 | 0 | 0.371 | |
P-p65 | ||||||||||||
Rho | −0.028 | 0.098 | 0.166 | 0.036 | −0.125 | 0.232 | 0.158 | 0.208 | 0.038 | 0.528 | 1 | 0.121 |
P | 0.825 | 0.444 | 0.194 | 0.778 | 0.33 | 0.067 | 0.215 | 0.102 | 0.768 | 0 | 0.343 | |
p65 Nuc | ||||||||||||
Rho | −0.047 | 0.034 | 0.017 | −0.06 | −0.146 | 0.075 | 0.022 | −0.026 | 0.019 | 0.115 | 0.121 | 1 |
P | 0.717 | 0.791 | 0.896 | 0.639 | 0.254 | 0.56 | 0.863 | 0.841 | 0.884 | 0.371 | 0.343 |
Abbreviations: p65 Cyto=cytoplasmic staining of p65; p65 Nuc=nuclear p65 staining; P-=phospho-; Rho=Spearman's coefficient correlation.
Significant correlations (P<0.05) are indicated by bold numbers.