Table 1. Clinicopathological features of patients.
Primary site | Pancreatic | Non-pancreatic | All |
---|---|---|---|
Number | 49 | 33 | 82 |
Median age (range) | 54.9 (24.4–81.6) | 57.4 (22.2–67.7) | 55.4 (22.2–81.6) |
Male | 27 | 15 | 42 |
Female | 22 | 18 | 40 |
Performance status | |||
0–1 | 44 | 27 | 71 |
⩾2 | 5 | 6 | 11 |
Site | |||
Lung | — | 8 | — |
GI tract | — | 9 | — |
Ovarian | — | 1 | — |
Unknown | — | 15 | — |
Differentiation | |||
Well | 36 | 21 | 57 |
Poorly | 9 | 9 | 18 |
Grade | |||
Low (1) | 4 | 4 | 8 |
Intermediate (2) | 31 | 16 | 47 |
High (3) | 5 | 10 | 15 |
Unknown | 9 | 3 | 12 |
Sites of metastases | |||
None | 5 | 4 | 9 |
Liver | 41 | 21 | 62 |
Lymph node | 13 | 14 | 27 |
Lung | 7 | 7 | 14 |
Bone | 6 | 5 | 11 |
Other | 10 | 6 | 16 |
Prior systemic therapy | |||
None | 33 | 24 | 57 |
Radionucleotide | 4 | 3 | 7 |
Embolisation | 3 | 0 | 3 |
Interferon | 2 | 1 | 3 |
Octreotide | 8 | 7 | 15 |
Radiotherapy | 0 | 1 | 1 |
Octreotide scintigraphy | |||
Positive | 39 | 18 | 57 |
Negative | 9 | 11 | 20 |
5HIAA urine | |||
Positive | 4 | 7 | 11 |
Negative | 21 | 16 | 37 |
Chromogranin A | |||
Positive (>60 U l−1) | 17 | 10 | 27 |
Negative (≤ 60 U l−1) | 9 | 10 | 19 |
Tumour type | |||
Non-functional | 38 | 31 | 69 |
Gastrinoma | 5 | 0 | 5 |
Glucagonoma | 4 | 1 | 5 |
Somatostatinoma | 1 | 1 | 2 |
Vipoma | 1 | 0 | 1 |
Abbreviations: GI=gastrointestinal; 5HIAA=5-hydroxyindoleacetic acid.