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. 2010 Jan 13;38(7):e94. doi: 10.1093/nar/gkp1215

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© The Author(s) 2010. Published by Oxford University Press.

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/2.5), which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 3. — Chromosome views of artificial profiles. Two samples (A and B) are shown for the following conditions (raw data, modified data and WACA corrected modified data) for chromosome 3. CBS-detected segments are represented by vertical lines on the right of each profile, respectively, showing gains underlined by filled rectangles. The nine modified probes are underlined across the profiles. As shown, while WACA in sample A allows a better delimitation of the artificial aberration, our algorithm allows the recovery of the same aberration in sample B after CBS segmentation.