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. 2010 Jan 11;38(7):2177–2189. doi: 10.1093/nar/gkp1219

Table 1.

HOE from PF00668 domain onto the unrelated PF00550

Iteration TPs Family coverage Tree coverage FPs Unrelated Pfam coveragea
1 271 0.11 0.14 0
2 998 0.49 0.93 0
3 478 0.19 0.93 113 PF00550 (10), CL61(1)
4 330 0.13 0.72 1784 PF00550 (1111) PF08415 (15) CL61 (1) CL28 (52) CL63 (14) PF00501 (4)
5 318 0.13 0.67 2174 PF00550 (1347/2855) PF08415 (19/140) PF02911 (1/8) CL28 (38/2153) CL63 (16/9791) CL46 (6/3586) PF00501 (4/1905)

aThe number of alignments to the unrelated family in the given iteration is shown in parenthesis. The size of the family is shown for the last iteration. The number of FPs is often less than the sum on the alignments that map to unrelated domains because sometimes over-extension in one sequence covered multiple unrelated domains.