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. Author manuscript; available in PMC: 2010 Oct 1.
Published in final edited form as: J Neurosci Res. 2009 Oct;87(13):2994–3001. doi: 10.1002/jnr.22126

Table I.

Intestinal Transit Times in Npc+/+ or +/−, Npc1−/− and GFAP-Npc1, Npc1−/− mice

GFAP-Npc1, Npc1−/−
Genotype Npc1+/+ or +/− Npc1−/− □ 100 days □ 100 days
Transit time without fasting (4) 192.5 ± 27.3 (3) 296.7 ± 37.9* (3) 202.7 ± 13.7 (3) 331.7 ± 47.3**
Transit time with fasting (4) 111.9 ± 5.9 (3) 144.2 ± 2.2* (2) 111.8 ± 1.3 ND
% body weight consumed
during study
(4) 4.3 ± 0.5 (3) 6.05 ± 0.44†† (2) 4.3 ± 0.75 ND

(n) ave. ± std. error

*

p □ 0.01 vs. Npc1+/+ or +/−

**

p □ 0.01 vs. □ 100 days

††

p □ 0.05 vs. Npc1+/+ or +/−

ND not determined