Fig. A.6.

Release of relaxing and contracting factors from endothelial cells and their effects on vascular smooth muscles. AC = adenylyl cyclase; ACE = angiotensin converting enzyme; ATP = adenosine triphosphate; A I = angiotensin I; A II = angiotensin II; cAMP = cyclic adenosine monophosphate; cGMP = cyclic guanosine monophosphate; COX = cyclo-oxygenase; ECE = endothelin converting enzyme; EDHE = endothelium-derived hyperpolarizing factor; eNOS = endothelial nitric oxide synthase; ET-1 = endothelin-1; GTP = guanosine triphosphate; NO = nitric oxide; $O_2^{-•}$ = superoxide anions; ${\mathrm{PGH}}_2$ = prostaglandin $H_2$; ${\mathrm{PGI}}_2$ = prostacyclin; R = receptor; sGC = soluble guanylyl cyclase; SR = sarcoplasmic reticulum; ${\mathrm{TAX}}_2$ = thromboxane $A_2$.

This figure is taken from [193].