Table 1.

Impact of Cholinergic agonists on sEPSC parameters

	Frequency, Hz	Peak Amplitude, pA	Rise Time (10–90%), ms	Decay Time (90–10%), ms
Baseline (8)	1.15 ± 0.22	15.22 ± 1.09	4.92 ± 0.48	25.89 ± 4.1
Paraoxon (3 μM)	1.70 ± 0.40*	23.35 ± 0.21*	4.74 ± 0.72	29.44 ± 5.86
Baseline (7)	0.75 ± 0.19	16.16 ± 0.19	2.90 ± 0.40	10.6 ± 1.30
Carbachol (50 μM)	1.14 ± 0.26**	15.30 ± 0.14**	3.03 ± 0.34	10.72 ± 1.28
Baseline (5)	1.49 ± 0.37	14.5 ± 2.74	3.38 ± 0.6	17.96 ± 5.90
Nicotine (1 μM)	1.84 ± 0.36*	15.55 ± 2.76*	3.43 ± 0.46	20.36 ± 7.71
Baseline (4)	0.58 ± 0.11	15.43 ± 1.89	2.31 ± 0.27	10.97 ± 1.01
Ambenonium (250 μM)	1.08 ± 0.31*	15.93 ± 2.02	2.26 ± 0.39	11.14 ± 1.63
Baseline (5)	0.69 ± 0.10	14.23 ± 1.73	3.54 ± 0.75	11.70 ± 0.43
Ambenonium (500 μM)	1.61 ± 0.70***	17.50 ± 1.80	2.49 ± 0.44	11.82 ± 2.10

Values are means ± SD. n are in parentheses. sEPSC, spontaneous excitatory postsynaptic potential.

^*P < 0.05;

^**P < 0.005;

^***P < 0.001.