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. 2010 Feb 3;298(4):F1051–F1058. doi: 10.1152/ajprenal.90202.2008

Table 1.

Summary of protocols for the different experiments showing duration of baseline and experimental periods, water intake, and drug dose for each experiment

Baseline Period, days Baseline Water Intake, ml/day Drug Dose, mg·kg−1·day−1 Treatment Period, days Treatment Water Intake, ml/day
Indomethacin 2 Free access 8 2 Free access
Ibu 2 Free access 40 2 Free access
Ibu/dehydration 2 Free access 40 2 0 (control, free access)
Ibu/FR 2 20 40 2 20
Ibu/FL 2 50 40 2 50
Mel/FR 2 20 1 2 20
Mel/FL 2 50 1 2 50
Mel/FL/FR 2 50 1 4 20

Ibu, ibuprofen; Mel, meloxicam; FL, fluid loaded; FR, fluid restricted.