Table 3.
Number of Days of Treatment | Fluid-Loaded Control | Fluid-Loaded Ibuprofen | P Value | |
---|---|---|---|---|
Urine output, ml/day | 1 | 29.7 ± 2 | 29.3 ± 1.1 | 0.93 |
2 | 27.5 ± 1.8 | 26.7 ± 1.6 | 0.86 | |
Urine osmolality, mosmol/kgH2O | 1 | 566 ± 25 | 556 ± 19 | 0.78 |
2 | 524 ± 16 | 517 ± 9 | 0.92 | |
Sodium, mmol/day | 1 | 0.7 ± 0.2 | 0.7 ± 0.1 | 0.99 |
2 | 0.8 ± 0.2 | 0.8 ± 0.1 | 0.85 | |
Potassium, mmol/day | 1 | 2.7 ± 0.3 | 2.2 ± 0.1 | 0.16 |
2 | 2.2 ± 0.2 | 2.2 ± 0.1 | 0.90 | |
Chloride, mmol/day | 1 | 1.7 ± 0.2 | 1.6 ± 0.03 | 0.61 |
2 | 1.7 ± 0.2 | 1.5 ± 0.1 | 0.65 | |
PGE, ng/day | 1 | 11.1 ± 2.2 | 9.4 ± 2.0 | 0.58 |
2 | 10.8 ± 2.0 | 9.5 ± 1.9 | 0.67 |
Values are means ± SE.