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Human renal proximal tubule (HK-2) cells infected with sphingosine kinase-1 (SK1)-encoding lentivirus (SK1-HK-2 cells) for 2 days show increased SK1 protein and mRNA expression (A) and increased SK1 activity [B; n = 4, *P < 0.05 vs. green fluorescent protein (GFP) control].
