Fig. 5.

A: CD boundary conditions at the OM-IM boundary for simulation 3 as a function of stage number. B: results from simulation 3: urine composition computed by mathematical model. C: experimental results redrawn from Fig. 4 in study by Gamble et al. (12). Terms are defined as in Fig. 1. In the simulation, urine flow at maximum osmolality was 0.12 nl·min⁻¹·nephron⁻¹; the experiment by Gamble et al., the corresponding urine flow was 0.13 nl·min⁻¹·nephron⁻¹.