Table 3.

Simulation 2: CD inflow conditions and resulting urine flow and content

				Urine
	CD Inflow*			Flow rate†
Stage	Na+, mM	Urea, mM	Osmolality, mosmol/kgH2O	nl/min	ml/day	Total osmolality, mosmol/kgH2O	Na+, mM	Urea, mM	NaCl+Urea, mosmol/kgH2O
1	11.99	735.6	772.8	0.151	16.5	1,467	41.40	1,300	1,337
2	51.78	675.1	788.1	0.119	13.0	1,609	76.96	1,339	1,440
3	93.10	611.8	803.4	0.114	12.5	1,641	144.4	1,226	1,455
4	139.8	560.8	841.6	0.108	11.8	1,729	247.3	1,081	1,504
5	206.8	546.2	956.4	0.118	12.9	1,719	314.8	951.8	1,502
6	275.2	491.6	1,032.9	0.130	14.2	1,611	382.4	737.1	1,419
7	339.1	407.8	1,071.1	0.112	12.3	1,508	414.7	552.2	1,299
8	406.9	316.8	1,109.4	0.112	12.3	1,399	447.1	393.6	1,204
9	478.5	218.5	1,147.7	0.103	11.3	1,305	476.6	242.9	1,113
10	464.6	9.468	994.6	0.119	13.0	1,043	413.8	132.0	889.4
11	395.8	0.0	765.1	0.148	16.2	732.2	333.6	11.3	624.8

^*At each stage, NR solute is present in CD inflow at a concentration of 20 mM multiplied by the percentage osmolality increase indicated in Table 2.

^†Urine flow rate is given in nl·min⁻¹·nephron⁻¹ and in ml·day⁻¹·animal⁻¹.