Table 4.

Simulation 3: CD inflow concentrations and resulting urine flow and content

			Urine
	CD Inflow*		Flow rate†
Stage	Na+, mM	Urea, mM	nl/min	ml/day	Total osmolality, mosmol/kgH2O	Na+, mM	Urea, mM	NaCl+Urea, mosmol/kgH2O
1	356.2	75.08	0.173	18.9	794.5	318.8	109.1	692.4
2	347.6	129.0	0.167	18.3	890.3	321.4	190.5	776.2
3	339.0	182.9	0.161	17.6	995.0	324.1	279.1	867.1
4	330.3	236.8	0.155	17.0	1,107	326.3	375.4	964.5
5	321.7	290.7	0.149	16.3	1,227	327.6	479.5	1,068
6	313.1	344.6	0.143	15.6	1,354	327.8	591.8	1,177
7	304.5	398.5	0.138	15.1	1,489	327.0	712.5	1,293
8	295.9	452.4	0.133	14.6	1,632	324.9	841.9	1,414
9	287.2	506.3	0.128	14.0	1,782	321.6	980.0	1,542
10	278.6	560.2	0.124	13.6	1,940	317.0	1,127	1,676
11	270.0	614.1	0.119	13.0	2,104	311.0	1,283	1,817

^*At stage 1, NR solute was present in CD inflow at a concentration of 20 mM and total CD inflow osmolality was 765.7 mosmol/kgH₂O. In each successive stage, NR solute concentration was increased by 1 mM. Thus at stage 11, NR solute concentration is 30 mM, and total osmolality was 1,148 mosmol/kgH₂O.

^†Urine flow rate is given in nl·min⁻¹·nephron⁻¹ and in ml·day⁻¹·animal⁻¹.