Figure 3.
EnvZc binding to OmpR using fluorescence anisotropy. The binding reactions contained 40 nM fluorescein-labeled OmpR. Closed triangles show OmpR binding to EnvZc with a Kd of 519 nM. The average Kd for EnvZc binding to OmpR from 10 independent experiments was 425 ± 127 nM. In the presence of specific DNA, EnvZc still binds OmpR, with a Kd of 568 nM (open triangles). The average Kd for EnvZc binding to OmpR C1-C2-C3 from six separate curves is 385 ± 162 nM. Reprinted with permission from [29].