Table 1.

Baroreflex parameters for normal and HF groups before and after intravenous irbesartan

	Normal		HF
	Control	After irbesartan	Control	After irbesartan
dBP vs. HR
Maximum slope	−4.2 ± 0.6	−5.3 ± 0.8	−2.78 ± 0.3*	−3.14 ± 0.6
Top plateau	153 ± 13	159 ± 7	125 ± 9*	118 ± 10
Bottom plateau	51 ± 3	52 ± 3	53 ± 4	57 ± 4
BP50	69 ± 3	58 ± 2†	70 ± 4	61 ± 2†
Threshold	84 ± 3	74 ± 3†	91 ± 4	77 ± 4†
Saturation	53 ± 5	43 ± 2†	50 ± 6	44 ± 2
dBP vs. CSNA
Maximum slope	−9.9 ± 3.2	−6.0 ± 1.3	−6.9 ± 1.1	−4.3 ± 0.6†
BP50	70 ± 2	61 ± 2†	74 ± 4	67 ± 4†
Threshold	83 ± 4	77 ± 3	87 ± 4	87 ± 7
Saturation	59 ± 4	46 ± 3†	61 ± 5	47 ± 5†

Values are means ± SE (n = 7). HF, heart failure; HR, heart rate; CSNA, cardiac sympathetic nerve activity; dBP, diastolic blood pressure; BP₅₀, pressure at 50% of maximum CSNA.

^*P < 0.05 vs. normal.

^†P < 0.05 vs. control.