TABLE 6.
Plasma triglyceride levels in nonfasted mice sacrificed at 140 ± 14 days
| Genotype | Sex | N | Total TG (mg/dl) | CM-TG (mg/dl) | VLDL-TG (mg/dl) | LDL-TG (mg/dl) | HDL-TG (mg/dl) |
|---|---|---|---|---|---|---|---|
| HL−/− | M | 5 | 69.47 ± 10.1 | 8.40 ± 2.7 | 37.59 ± 6.5 | 14.95 ± 0.9a,b | 8.54 ± 0.4a |
| HL+/+ | M | 4 | 71.09 ± 10.8 | 10.34 ± 3.5 | 38.36 ± 6.4 | 17.57 ± 1.2a | 4.82 ± 0.4b |
| HL−/−,+S | M | 4 | 42.38 ± 2.3 | 4.95 ± 2.2 | 22.91 ± 0.8 | 11.38 ± 0.8b | 3.15 ± 0.1c |
| Overall P | NS | NS | NS | 0.006 | <0.0001 |
CM-TG, chylomicron-triglyceride; HDL-TG, HDL-triglyceride; LDL-TG, LDL-triglyceride; TG = triglyceride; VLDL-TG = VLDL-triglyceride. All animals are ≥N10. HL−/− and HL−/−,+S mice are littermates. HL+/+ mice are from a backcross between N10 HL+/+,+S and HL+/+ mice. Data presented are means ± SEM. Analyses were run on natural log transformed data. For posthoc analysis, sexes were analyzed separately. Values not sharing superscript (a,b,c) are different by Scheffe's posthoc test (P < 0.05).