Evaluation of the AA levels and IBS symptom severity according to the presence or absence of psychiatric comorbidity. (4A) AA levels in mild, moderate, and severe IBS. (4B) AA levels in IBS patients with and without psychiatric comorbidity. AA, arachidonic acid; FAME, fatty acid methyl esters; IBS, irritable bowel syndrome; IBS+, IBS with psychiatric comorbidity; IBS−, IBS without psychiatric comorbidity.