TABLE 1.

PUFA concentrations (g/100 g FAME), ω-6:ω-3 ratio, and eicosanoid concentrations (pg/ml) in IBS according to disease subtype and status.

	Disease Subtype				Disease Status
Parameter	D-IBS	C-IBS	A-IBS	F, (df), P	CA	RA	Q	F, (df), P
Total ω-6	33.16 ± 0.86	32.39 ± 0.94	32.69 ± 0.76	0.13, (3,63), 0.95	32.47 ± 0.49	32.05 ± 0.87	35.19 ± 1.19	1.88, (3,63), 0.14
Total ω-3	4.49 ± 0.30	5.36 ± 0.78	5.02 ± 0.56	1.98, (3,63), 0.13	5.04 ± 0.43	5.20 ± 0.66	4.07 ± 0.38	2.22, (3,63), 0.09
ω-6:ω-3	7.89 ± 0.71	7.06 ± 1.56	8.27 ± 1.07	1.10, (3,63), 0.36	7.51 ± 0.88	8.81 ± 1.23	9.34 ± 0.94	1.24, (3,63), 0.30
AA	8.39 ± 0.41	8.05 ± 0.54	8.81 ± 0.42	2.03, (3,63), 0.12	9.09 ± 0.54	7.90 ± 0.60	8.63 ± 0.54	3.02, (3,63), 0.04a
PGE2	1835 ± 362.8	1115 ± 202.4	1500 ± 187.5	3.42, (3, 40), 0.03a	1531 ± 364	1431 ± 142.6	1655 ± 527.6	2.41 (3, 40), 0.08
LTB4	339 ± 83.57	331.2 ± 66.57	331 ± 31.33	1.53, (3, 33), 0.22	361 ± 78.51	319.7 ± 38.34	324.3 ± 65.99	1.65 (3, 33), 0.2

^aP < 0.05, one way ANOVA.

Abbreviations: AA, arachidonic acid; A-IBS, alternating IBS; C-IBS, constipation-predominant IBS; CA, currently active; D-IBS, diarrhea-predominant IBS; FAME, fatty acid methyl esters; LTB₄, leukotriene B₄; PGE₂, prostaglandin E₂; PUFA, polyunsaturated fatty acid; Q, quiescent; RA, recently active.