TABLE 1.
Subject characteristics (n = 5418)
| Study Characteristics Mean (SD)a | Men (n = 2,621) | Women (n = 2,797) |
|---|---|---|
| Age (years) | 75.0 (3.3) | 75.6 (3.4)b |
| BMI (kg/m2) | 26.6 (3.6) | 27.1 (4.6)b |
| History diabetes mellitus, n (%) | 324 (12.4) | 251 (9.0)b |
| History hypertension, n (%) | 1333 (50.9) | 2027 (72.5)b |
| History vascular disease, n (%) | 1371 (52.3) | 1033 (36.9)b |
| History of MI, n (%) | 508 (19.4) | 222 (7.9)b |
| Current smoking, n (%) | 847 (32.3) | 586 (21.0)b |
| Alcohol consumption, n (%) | 1851 (70.6) | 1165 (41.7)b |
| TC (mg/dl) | 207.0 (30.7) | 231.9 (34.5)b |
| LDL-C (mg/dl) | 138.5 (27.8) | 154.9 (35.3)b |
| HDL-cholesterol (mg/dl) | 45.6 (12.2) | 53.0 (13.4)b |
| Triglyceride (mg/dl) | 132.4 (64.3) | 140.6 (59.4)b |
| apoA-I (mg/dl) | 124.4 (22.2) | 139.9 (24.1)b |
| apoB (mg/dl) | 110.6 (21.3) | 119.1 (22.6)b |
| apoE 2/2 + 2/3 (%) | 13.05 | 11.30 |
| apoE 3/3 (%) | 63.1 | 65.7 |
| apoE 3/4 + 4/4 (%) | 23.8 | 23.0 |
BMI, body mass index.
a
Means (SD) unless otherwise specified; differences between men and women were assessed using a t-test for continuous traits and χ2 test for binary traits.
b
P < 0.001, apoE 2/4 carriers were excluded (see Materials and Methods).