Table 1.
Condensed data on patients histories and sample type
| Gender | Age | Underlying disease |
Year of Tx. |
Kidney explant or biopsy |
Why indicated ? |
Histo- pathological diagnosis |
Tissue samples analyzed n = |
Symbol#in Figure 8 |
|---|---|---|---|---|---|---|---|---|
| female | 60 | Systemic Lupus erythematosus | 1999* | Kidney explant (01/2007) |
Acute renal failure |
(Interstitial fibrosis, tubular atrophy) Banff 2007, 5. II [34] |
2 | Black circle Black square |
| female | 41 | Systemic vasculitis (Purpura Schoenlein-Henoch) | 1996 | Kidney explant (01/2007) |
Acute renal failure |
(Interstitial fibrosis, tubular atrophy) Banff 2007, 5. II [34] |
1 | Black triangle |
| male | 17 | Obstructive uropathy |
2006* | Kidney explant (08/2007) |
Impaired kidney function |
(Interstitial fibrosis, tubular atrophy) Banff 2007, 5. III [34] |
2 | Black reverse triangle Black rhomb |
| female | 45 | Chronic glomerulo-nephritis | 1996 | Indication biopsy (04/2007) |
Impaired kidney function |
Chronic tubulo-interstitial injury, evidence for calcineurin inhibitor toxicity (CNIT) |
1 | White circle |
| male | 72 | Chronic interstitial nephritis | 2007 | Indication biopsy (06/2007) |
Impaired kidney function |
Interstitial fibrosis, tubular atrophy, vasculopathy) Banff 2007, 5. II [34] ** |
1 | White square |
| female | 42 | Systemic Lupus erythematosus | 2005 | Kidney explant (2005) |
Allograft-steal-syndrome | Diffuse tubular damage |
2 | Black circles in plot "Control" |
| Not known (anonymized) |
RCC | n.a. | Tumor nephrectomy |
RCC | Normal | 1 | ||
| RCC | RCC | 1 | ||||||
| RCC | RCC | 1 | ||||||
2nd allograft in patients history, ** = "old-for-old" kidney allocation, Tx. = transplantation, RCC = renal cell carcinoma, n.a. = not attributable. #Two symbols per case mean that 2 different tissue blocks were analyzed in the same patient.