Table 2.
Demographic and clinical information for subjects used for Luminex analysis. Data is presented as mean ± SEM.
| Healthy Volunteers (n = 10) | ICP ≤20 mm Hg (n = 9) |
ICP ≥25 mm Hg (n = 10) | |
|---|---|---|---|
| Age range | 20-39 years | 19-51 years | 14-54 years |
| Age (average) | 26.5 ± 5.5 years | 29.5 ± 12.1 years | 29.3 ± 11.2 years |
| Gender | 8 male | 6 male | 9 male |
| 2 female | 3 female | 1 female | |
| Race | 8 Caucasians | 8 Caucasians | 9 Caucasians |
| 1 African-Americans | 1 African-Americans | 1 African-American | |
| 1 Asian | |||
| Ethnicity | 5 non-hispanics | 6 non-hispanics | 6 non-hispanics |
| 5 non-hispanics | 3 hispanics | 4 hispanics | |
| Apache II score | N/A | 17.6 ± 3.7 | 21.2 ± 3.5 |
| ISS | N/A | 23.6 ± 5.4 | 19.8 ± 3.6 |
| Therapy intensity level | |||
| first 24 hr | N/A | 4.0 ± 1.8 | 5.1 ± 4.1 |
| 72-120 hr | N/A | 3.2 ± 1.8 | 5.2 ± 4.0 |
| Mortality at time of discharge | N/A | 0/9 (0%) | 2/10 (20%) |
| Mechanism of injury | N/A | ||
| motorcycle collision | 3/9 (33%) | 3/10 (30%) | |
| motor vehicle accident | 5/9 (55%)a | 5/10 (50%) | |
| fall | 0/9 (0%) | 2/10 (20%)b | |
| assault | 1/9 (11%) | 0/10 (0%) | |
| Initial CT resultsc | N/A | ||
| skull fracture | 5/9 (56%) | 5/10 (50%) | |
| subarachnoid hemorrhage | 6/9 (67%) | 7/10 (70%) | |
| epidural hematoma | 3/9 (33%) | 1/10 (10%) | |
| subdural hematoma | 3/9 (33%) | 8/10 (80%) | |
| intraventricular hemorrhage | 4/9 (44%) | 3/10 (33%) | |
| contusion | 7/9 (78%) | 8/10 (80%) | |
| midline shift | 3/9 (33%) | 3/10 (30%) | |
| edema | 5/9 (56%) | 3/10 (30%) | |
| diffuse axonal injury | 0/9 (0%) | 1/10 (10%) | |
a, one subject was assaulted after motor vehicle accident
b, one subject fell off a moving vehicle
c, some patients may present with more than one pathology.