Table 5.
Diagnostic accuracy of IL-6 for predicting subsequent elevations in ICP in patients with polytrauma.
| Maximum ICP (mm Hg) | IL-6 (pg/ml) | Classification | Actual | |
|---|---|---|---|---|
| 1 | NA | undetectable | HV | HV |
| 2 | NA | 2.06 | HV | HV |
| 3 | NA | 1.44 | HV | HV |
| 4 | 11 | >600 | ICP ≥ 25 mm Hg | ICP ≤ 20 mm Hg |
| 5 | 16 | 140.28 | ICP ≥ 25 mm Hg | ICP ≤ 20 mm Hg |
| 6 | 20 | 50.01 | ICP ≤ 20 mm Hg | ICP ≤ 20 mm Hg |
| 7 | 20 | 518.70 | ICP ≥ 25 mm Hg | ICP ≤ 20 mm Hg |
| 8 | 12 | 75.00 | ICP ≤ 20 mm Hg | ICP ≤ 20 mm Hg |
| 9 | 34 | 85.21 | ICP ≤ 20 mm Hg | ICP ≥ 25 mm Hg |
| 10 | 32 | 342.89 | ICP ≥ 25 mm Hg | ICP ≥ 25 mm Hg |
| 11 | 28 | 189.76 | ICP ≥ 25 mm Hg | ICP ≥ 25 mm Hg |
| 12 | 38 | 30.91 | ICP ≤ 20 mm Hg | ICP ≥ 25 mm Hg |
| 13 | 34 | 236.90 | ICP ≥ 25 mm Hg | ICP ≥ 25 mm Hg |
| 14 | 26 | 466.18 | ICP ≥ 25 mm Hg | ICP ≥ 25 mm Hg |
Blinded samples taken within the first 16 hr of injury (or from paired healthy volunteers) were analyzed for IL-6 content. Serum IL-6 concentrations could be used to correctly identify only 6 of the 11 polytrauma patients tested (54%). HV: healthy volunteer.