Table 3.
Subjective markers of laxation
| Pullulan | Resistant Starch | Soluble fiber dextrin | Soluble Corn Fiber | 10-DE maltodextrin (placebo) | p value2 | |
|---|---|---|---|---|---|---|
| Gastrointestinal symptoms1 | ||||||
| Bloating | 3.9 ± 0.4a | 2.8 ± 0.4b | 2.8 ± 0.4b | 3.1 ± 0.4a, b | 2.2 ± 0.3b | 0.0040 |
| Cramping | 2.8 ± 0.4a | 2.3 ± 0.4a, b | 2.0 ± 0.3a, b | 1.8 ± 0.3b | 1.5 ± 0.2b | 0.0269 |
| Flatulence | 5.1 ± 0.4a | 3.9 ± 0.4b | 4.0 ± 0.4b | 4.2 ± 0.4b | 2.8 ± 0.3c | <0.0001 |
| Stomach noises | 3.4 ± 0.4a | 3.2 ± 0.4a | 2.6 ± 0.3a, b | 2.9 ± 0.3a | 2.0 ± 0.2b | 0.0075 |
| GI score | 3.8 ± 0.4a | 3.0 ± 0.4a, b | 2.8 ± 0.4b, c | 3.0 ± 0.4b | 2.1 ± 0.2c | 0.0036 |
| Stool consistency (self-reported)1 | 2.1 ± 0.1 | 2.2 ± 0.1 | 2.1 ± 0.1 | 2.0 ± 0.1 | 2.2 ± 0.1 | 0.6715 |
| Stool consistency (investigator-reported) | 2.5 ± 0.2 | 2.4 ± 0.2 | 2.5 ± 0.2 | 2.3 ± 0.2 | 2.5 ± 0.2 | 0.4333 |
Values reported as treatment means ± SEM, adjusted for visit. Symptoms were each rated on a 10-point scale (1 = minimal, 10 = excessive). The GI score is the mean of bloating, cramping, flatulence and stomach noise ratings (possible range 1–10). Self-reported stool consistency was rated on a 10-point scale (1 = diarrhea, 10 = hard). The scale was adjusted to a 4-point scale to coincide with investigator-reported stool consistency Investigator-reported stool consistency was rated on a scale from 1 to 4: 1 = hard and formed, 2 = soft and formed, 3 = loose and unformed, 4 = liquid [9]. p values represent differences between treatments. Treatments with different letters are significantly different.
Data from day 3 and day 14 did not differ significantly, so the days were pooled for analysis.